Trained at the National Ballet School of Albania, Igli Mezini danced as a soloist at the National Theater of Tirana, Cannes Jeune Ballet, Hessisches Staatsballett Wiesbaden, Ballet Preljocaj, compagnie Linga, and TanzLuzern. He collaborated with choreographers Jiří Kylián, Jean-Christophe Maillot, Marcos Morau, Angelin Preljocaj, Alexander Ekman, Jérôme Bel, Cayetano Soto, Crystal Pite, Marco Goecke, Wayne McGregor, Hofesh Schechter, Po Cheng Tsai, Ella Rothschild, Katarzyna Gdaniec, Marco Cantalupo, Muhammed Kaltuk, Tom Weinberger amongst others. He has taught and led workshops in Europe, South America, Asia and Australia, and currently continues to collaborate internationally as a dancer, teacher and assistant.